【摘要】 目的评价伊贝沙坦对心房颤动(房颤)患者恢复窦性心律(复律)后的维持作用。方法持续性房颤患者52例,随机分为两组各26例。两组经正规抗凝治疗3周后均给予胺碘酮200mg,q8h,用1周后继以200mg,q12h,1周后改为200mg·d1,治疗组同时给予伊贝沙坦150mg·d1。分别观察两组中成功复律者中的复发率。结果随访6个月,治疗组复律19例中有2例复发,17例维持窦性心律;对照组复律17例中有8例复发,9例维持窦性心律。治疗组房颤复发率低于对照组(P<005)。结论伊贝沙坦能降低房颤复发率,有效维持窦性心律。更多还原

【Abstract】 Objective To evaluate the effect of irbesartan to maintain sinus rhythm in patients with durative atrial fibrillation after cardioversion. Methods Fifty-two patients with durative atrial fibrillation were randomized into two equal groups. Group I were treated with amiodarone, and group Ⅱ were treated with amiodarone plus irbesartan. The reoccurence of atrial fibrillation was observed in all the patients for 6 mo after cardioversion. Results The reoccurence of atrial fibrillation in group I was higher than that in group Ⅱ. Conclusion The results suggest that irbesartan may reduce the reoccurrence of atrial fibrillation and be efficacious in maintaining sinus rhythm.更多还原