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CTAC介导化学发光测定马来酸氯苯那敏
CTAC-Based Chemiluminescence Determination of Chlorpheniramine Maleate
【摘要】 建立了一种测定马来酸氯苯那敏的新方法 .在优化的实验条件下 ,测定马来酸氯苯那敏的线性范围为 0 .3~ 30 μg/mL ,检出限 ( 3σ)为 45ng/mL ,对浓度为 3μg/mL的马来酸氯苯那敏进行 1 1次平行测定 ,其RSD为 2 .5 1 % .将本法用于药片和注射液的测定 ,结果令人满意 .
【Abstract】 A new chemiluminescence (CL) method is proposed for the determination of chlorpheniramine maleate in this paper. In the optimum conditions, CL intensities are proportional to concentrat ions of the studied drug over the range 0.3~30 μg/mL with a detection limit of 45 ng/mL. The relative standard deviation (RSD) is 2.51% for 3 μg/mL chlorphenira m ine maleate (n=11). The method has been applied to the determination of tablets and injection with satisfactory results.
【关键词】 逆胶束;
化学发光;
马来酸氯苯那敏;
药物分析;
【Key words】 revered micellar; chemiluminescence; chlorpheniramine maleate; pharma ceutial a nalysis;
【Key words】 revered micellar; chemiluminescence; chlorpheniramine maleate; pharma ceutial a nalysis;
- 【文献出处】 渝西学院学报(自然科学版) ,Journal of Western Chongqing University , 编辑部邮箱 ,2005年01期
- 【分类号】TQ463
- 【被引频次】1
- 【下载频次】101