【摘要】 [目的]观察接种乙肝疫苗后的免疫效果,减少HBV感染,达到消除乙肝的目的。[方法]2001年1月至2004年12月,在阳泉市第三人民医院就诊的乙肝病人的接触者(高危人群)中,筛选肝功能正常、乙肝“五项”指标阴性的569人,接种乙肝疫苗,检测抗HBs。[结果]观察对象接种乙肝疫苗后抗HBs阳性率为82.6%,阴性者加强免疫后有27.3%阳转,观察对象阳性率提高到87.3%。[结论]接种乙肝疫苗能显著提高高危人群抗HBs阳性率。更多还原

【Abstract】 [Objective]To evaluate the therapeutic effectiveness of hepatitis B (HB) vaccine after vaccination, reduce HBV infection and eliminate HB occurrence . [Methods]569 clinical cases of HB patient contacts in No.3 People’s Hospital of Yangquan City between January 2001 and December 2004,a high risk group with normal liver function and negative indexes in the 5-item test of HB , were screened and injected HB vaccine.An HBsAg test was later conducted to evaluate the therapeutic effectiveness of HB vaccine.[Results]The positive rate of HBsAg of the objects of observation receiving HB vaccine was 82.6%. 27.3% of the cases with HBsAg(-)revealed HBsAg(+).The positive rate of HBsAg of the objects of observation increased to 87.3%.[Conclusion]HB vaccine has a notable effect on the increase in positive rate of HBsAg of the high risk group.更多还原