【摘要】 目的调查某院1000例高血压患者门诊处方,了解高血压病人常用降压药物的种类和降压治疗方案,评估它们是否符合国际高血压治疗指南。方法抽查2004年8~12月某院心内科专科1000例高血压病人门诊处方,详细地进行统计及分析。结果门诊高血压病人常用降压药物为:钙拮抗剂(CCB)38.5%,血管紧张素转换酶抑制剂(ACEI)24.8%、β受体阻滞剂(β-Blocker)18.3%、利尿剂12.0%和血管紧张素II受体拮抗剂(ARB)6.3%。其中CCB、利尿剂以国产为主,β受体阻滞剂、ACEI、ARB以进口居多。在1000例病人中,采用一种降压药物占60.6%,联合应用2种或2种以上降压药物占39.4%。结论门诊高血压病人降压药物应用种类及降压治疗方案基本符合2003年美国和欧洲高血压治疗指南,但也存在利尿剂应用偏少及可能存在降压药物用量不足等问题。更多还原

【Abstract】 Objective to investigate the prescriptions of 1000 hypertensive outpatients, find out the classes of antihypertensive drugs in common use and the scenarios for drug choices in our hospital, and evaluate whether they were accorded with the international hypertension therapy guidelines. Methods The prescriptions of selected 1000 outpatients with hypertension visiting our hospital from August to December of 2004 were analyzed. Results The antihypertensive drugs prescribed to these outpatients with hypertension usually included: Calcium Channel Blockers (CCB) 38.5%, Angiotensin Converting Enzyme Inhibitors (ACEI)24.8%,β-Adrenergic Receptor Blockers (βBlocker) 18.3%, Diuretics 12.0%, and AT1-Receptor Blockers (ARB) 6.3%. Compared with CCB and Diuretics chiefly made in our country, βBlocker, ACEI and ARB taken by these hypertensives were mostly imported. 60.6 percent of all these 1000 patents took only one class of antihypertensive drugs. The rest of the patients took the combination of two or more than two classes of antihypertensive drugs. Conclusion The classes of antihypertensive drugs were prescribed and antihypertensive therapy in our hospital were accorded with the 2003 American & European Hypertension Therapy Guidelines in general. But there were still have some problems. For example, the application of Diuretics was not as extensive as it could be. Possibly existing insufficient medication was another problem.更多还原