【Abstract】 Objective To evaluate the efficacy of erythropoietin in prevention and treatment of anemia of prematurity. Methods 119 preterm infants were randomly assigned to receive (treated group,60 neonates) or not to receive(control group, 59 neonates) rhEPO. RhEPO (750IU·kg -1·w -1)was given three times weekly for 4 weeks.Both these two groups received iron and folic acid.Results Treated group had a marked increase of reticulocyte compared with the control group (P<0.01).There were statistically significant differences between these two groups in the rate of weight gain(P<0.05).Condusion Early administration of high dosage of rhEPO can lighten the degree of anemia in neonate更多还原