【摘要】 目的:从病理学角度分析120例幽门螺杆菌阳性慢性浅表性胃炎(chronic superficial gastritis,CSG)的组织学特征。方法:用电子胃镜对确诊的120例幽门螺杆菌阳性CSG患者的炎症活动性、慢性炎症、血管病变、上皮损伤、腺体萎缩、不典型增生及肠化生等组织形态学指标进行回顾性分析。结果:CSG病人的黏膜具有急性炎症、慢性炎症、血管病变、上皮损伤,分别高达97．5％(117／ 120)、98．3％(118／120)、95．8％(115／120)、70％(84／120),腺体萎缩、不典型增生及肠化生的发生率约为35％-39．2％,组织学改变均以1级占多数。结论:急、慢性炎症细胞浸润,血管病变及上皮损伤是幽门螺杆菌阳性CSG的组织学基础,其慢性黏膜病变的组织学改变均以1级为主。更多还原

【Abstract】 Objective: To investigate the histopathological changes of gastric mucosa in chronic superficial gastritis (CSG). Methods: 120 patients with helicobacter pylori ( Hp) positive CSG proven by endoscopy were enrolled into the study. Acute inflammation activity, chronic inflammation, vascular pathological changes, epithelium injury, mucosal atrophy, atypical hyperplasia and intestinal metaplasia were observed. Results: Acute and chronic inflammation were found in 117 cases and 118 cases (97.5% , 98. 3% ) , vascular pathological changes was found in 115 patients(95. 8% ) , epithelium injury of gastric mucosa was found in 84 cases (70% ). The rate of mucosal atrophy, atypical hyperplasia and intestinal metaplasia were observed in 35% -39. 2% of patients. Most of them were in grade 1 of changes. Conclusion: Acute and chronic infiltration of inflammatory cells of gatric mucosa, vascular pathological changes, as well as epithelium injury were the main basic histological changes of Hp positive CSG. Mild-grade of mucosal atrophy, atypical hyperplasia and intestinal metaplasia were also associated with Hp positive CSG.更多还原