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纳络酮治疗中、重度新生儿缺氧缺血性脑病的疗效观察

Clinical observation on the curative effect of naloxone for moderate and se vere neonate hypoxic ischemic encephalopathy

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【作者】 何永忠陈海珠官玲燕林瑞云

【Author】 HE Yong-zhong,CHEN Hai-zhu,GUAN Liny-an,et al. (The Longhu People’s Hospital of Shantou,Guangdon515041,China)

【机构】 汕头市龙湖人民医院儿科汕头市龙湖人民医院儿科 广东汕头515041广东汕头515041广东汕头515041

【摘要】 目的:观察纳络酮治疗新生儿缺氧缺血性脑病的疗效。方法:62例中、重度新生儿缺血缺氧性脑病(HIE)分为治疗组32例、对照组30例,在常规综合治疗的基础上,治疗组加用纳络酮静脉注射和静脉点滴,连用3~5天。结果:治疗组总有效率90%,对照组总有效率66%(P<0.05)。结论:纳络酮治疗HIE疗效显著。

【Abstract】 Objective:To evaluate the curative effect of naloxone for trea ti ng moderate and severe neonate hypoxic-ischemic encephalopathy(HIE).Methods:62 cases moderate and severe of HIE were randomly divided into treatment group and c ontrol group,and both groups received combining treatment.Injection of naloxone was added in the treatment group,3~5days as a course of treatment.Results:The total effective rate was90.0%in the treatment group and66%in the control group , with a significant difference between two groups(P<0.05).Conclusion:Naloxone i s effective in treating moderate and severe HIE.

【关键词】 纳络酮新生儿缺氧缺血性脑病
【Key words】 HIENeonateNaloxone
  • 【文献出处】 现代医药卫生 ,Modern Medicine Health , 编辑部邮箱 ,2005年16期
  • 【分类号】R722.1
  • 【被引频次】1
  • 【下载频次】19
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