【摘要】 目的:探讨监测中、老年体内氧化/抗氧化状态以及血脂、空腹血糖水平的临床意义。方法:测定青年对照组及中、老年人血清丙二醛(MDA),超氧化物歧化酶(SOD),谷胱甘肽过氧化物酶(GSH-PX),总抗氧化能力(T-AOC)及血总胆固醇(CHO)、低密度脂蛋白(LDL)、高密度脂蛋白(HDL)、甘油三酯(TG)和空腹血糖(FBG)。结果:中、老年人组MDA、CHO、LDL、TG、FBG明显高于青年组,且老年组又明显高于中年组。中、老年人组中SOD、GSH-PX、T-AOC明显低与青年组,且老年组中SOD、T-AOC较中年组下降也有显著差异。结论:在中、老年人群中除血脂、血糖水平外,MDA、SOD、T-AOC、GSH-PX等几项指标也是评价中、老年人体内氧化应急、氧化/抗氧化能力客观指标,监测其水平,对老年病的防治具有很大的价值。更多还原

【Abstract】 Objective:In order to examine the related factors which lead t o t he aged disease,the state of oxidant/antioxidant,the content of blood lipid,b lood sugar were investigated.Methods:3groups taken part in this survey were test ed for the serumMDA,SOD,GSH-PX,T-AOC,blood lipid and fasting blood glucose, the tests between young controls and middle and aged groups were compared.Result s:The serumMDA,SOD,LDL,TG,FBG in middle and aged groups were significantly h igher than those in normal controls,which in the aged group were higher than th ose in the middle age group.The serum SOD,GSH-PX,T-AOC in middle and aged grou ps were lower than those in young controls.And the SOD,T-AOC in aged group were lower than those in middle age group.Conclusion:Apart from measuring the blood l ipid and fasting blood glucose,it is also important to measure serum MDA,SOD, GSH-PX,T-AOC levels for monitoring the state of oxidant/antioxidant and prevent ing senile disease.更多还原