【摘要】 目的探讨血浆同型半胱氨酸(Hcy)水平与脑梗死的关系。方法73例脑梗死根据病灶大小分二组:大片梗死27例,小片梗死46例。同时检测血浆Hcy、叶酸、VitB12水平。分析血浆Hcy水平与中风的危险因素、病灶大小及血清叶酸、VitB12的关系。结果血浆Hcy水平与高血压、糖尿病、血脂、性别、年龄各指标无明显相关关系,但与梗死病灶大小有关,同时发现与血清叶酸、VitB12呈负相关。结论Hcy水平与脑梗死病灶大小有关,高血浆Hcy血症可能是动脉粥样硬化性脑梗死的危险因素。更多还原

【Abstract】 Objective To study the relations between plasma homocysteine (Hcy) and cerebral infarction.Methods 73 cerebral infarction patients were divided into two subgroups:large infarction (27),small infarction (46).The relations between Hcy and hypertension,diabetes,blood lipid,sex,age,the size of cerebral infarction,vitaminB 12, serum folic acid were analyzed.Results Relations between Hcy and hypertension,diabetes,blood lipid,sex,age were not significant.There were correlations between Hcy and the size of cerebral infarction.Negative correlation was found between Hcy and the level of vitaminB 12 and serum folic acid. Conclusion Plasma Hcy level had a close correspondence with the size of cerebral infarction.It suggested that high level of Hcy may be the risk factor of carotid atherescleretic cerebral infarction.更多还原