【摘要】 目的探讨肺炎衣原体(CP)感染与急性冠脉综合征(ACS)的相互关系。方法应用固相酶联免疫吸附(ELISA)方法定量检测130例ACS患者、40例非ACS患者和50例健康者血清CP特异性抗体IgG,并同时应用乳胶颗粒凝集试验进行CRP测定。结果CP抗体和CRP阳性率在ACS组明显高于非ACS组和健康组,和健康组比较,P<0.01和P<0.05。结论CP感染可能通过影响动脉粥样硬化斑块的稳定性而增加ACS的危险性。更多还原

【Abstract】 Objective To investigate the relationship between chlamydia pneumoniae (CP) and acute coronary syndrome (ACS). Methods CP-specific IgG antibodies were measured by enzyme linked immunosorbent assay (ELISA) and C-reactive protein (CRP) were measured by latex particle agglutination test (LPAT) in 130 cases of ACS and 40 cases of non-ACS and 50 healthy control. Results The rate of seropositive for CP and CRP was significantly higher in the ACS group than the non-ACS group and healthy control group(P<0.01 and P<0.05 respectively=. Conclusion CP infection may increase the risk of ACS by influencing stability of atherosclerosis plaque.更多还原