节点文献
血管平滑肌细胞表型转化及相关信号转导机制探讨
Explore on Phenotype Transforming and Related Mechanisms of Signal Transduction in Vascular Smooth Muscle Cell
【摘要】 血管平滑肌细胞增殖是血管成形术后再狭窄、动脉粥样硬化斑块形成的病理基础。血管平滑肌细胞增殖能力与其表型转化密切相关。对从血管平滑肌细胞表型转化的主要特征、标志物、信号转导机制进行了探讨。
【Abstract】 Vascular smooth muscle cell proliferation is a pathological basis of restenosis after percutaneous transluminal coronary angioplasty and atherosclerotic lesion formation.Vascular smooth muscle cell proliferative ability is significantly associated with its phenotype transforming.This article explores main character,markers,signal transduction mechanism of phenotype transforming.
【关键词】 表型转化;
信号转导;
血管平滑肌细胞;
MAPK级联途径;
PI-3-K通路;
【Key words】 Phenotype transforming; Signal transduction; Vascular smooth musle cell; MAPK cascade pathway; PI-3-K pathway;
【Key words】 Phenotype transforming; Signal transduction; Vascular smooth musle cell; MAPK cascade pathway; PI-3-K pathway;
【基金】 国家自然科学基金资助项目(30271674)
- 【文献出处】 心血管病学进展 ,Advances In Cardiovascular Diseases , 编辑部邮箱 ,2005年02期
- 【分类号】R329.2
- 【被引频次】42
- 【下载频次】1159