【摘要】 目的:探讨2型糖尿病患者糖尿病肾病(DN)的相关因素。方法:对556例2型糖尿病患者慢性并发症的资料进行回顾性分析,采集患者的人口统计学指标(如年龄、性别、、职业、文化水平、糖尿病家族史等)、人体指标(如入院时收缩压、舒张压等)、实验室指标(如低密度脂蛋白、高密度脂蛋白、载脂蛋白、纤维蛋白原、糖化血红蛋白等),对DN组资料采用多因素Logistic回归进行分析,得出与DN发病的相关因素。结果:在多因素Logistic回归分析中具有统计学意义的保护因素为HDL-C和ApoAI;危险因素为病程和HbA1c;糖网、糖尿病周围神经病变患者发生DN的风险增加。结论:病程长、平均血糖高的糖尿病患者发生DN的危险增加;HDL-C和ApoAI高的患者发生DN的风险大。糖网和糖尿病周围神经病变患者发生DN的机率增加。更多还原

【Abstract】 Objective: To investigate the correlation factor of diabetic nephro-pathy（DN） in type 2 diabetes.Methods: Collecting,age,sex,occupation,level of culture,family history of diabetes,course of hypertention,SBP and DBP on admission,LDL,HDL,ApoAI,ApoB,Apoa,FIB,HbA1c,etc.The date were studied with binary logistic regression,finding the relative factors of diabetic nephropathy.Result: Course of disease and HbA₁c are risk factors,HDL-C and ApoAI are protective factors.The diabetic retinopathy and diabetic peripheral neuropathy are positive correlation to DN.Conclusion: The patients who are longer couse of diabetes and higher level of HbA1c have higher risk of DN;The patients who are at higher level of HDL and ApoAI have lower risk of DN;The patients having abnormality of electromyogram and diabetic retinopathy more likely suffer DN.更多还原