【摘要】 目的:探讨妊娠期肝内胆汁淤积症(ICP)孕妇肝功能变化与围生儿预后的关系。方法:对我院1998 年~2004年5月确诊为ICP的143例孕妇临床资料进行回顾性分析。结果:血清谷丙转氨酶(ALT)>40 U/L、总胆红素(TBIL)>28μmol/L的孕妇,羊水污染及新生儿窒息发生率增加,且ALT水平越高,其发生率越高。结论:ICP孕妇ALT及TBIL水平升高者胎儿预后不佳,必须高度重视,严密监护,适时终止妊娠。更多还原

【Abstract】 Objection: To investigate the relationship between hepatic function of mothers and prognosis of fetus in intraheptic cholestasis of pregnancy. Methods: Retrospective study of 143 patients with ICP. Results: The incidence of meconium passage and fetal distress were perfectly high in mothers of high serum transaminase and bilirubin. The higher of ALT level, the higher of its incidence rate. Conclusion:The faetal prognosis of mothers with high level serum transaminase and bilirubin is bad, so they must be taken great aware of and monitored closely, the pregnancy should be ended timely.更多还原