【摘要】 孕妇血清HBV-DNA、HBeAg阳性和胎盘绒毛毛细血管内皮细胞乙型肝炎病毒感染是乙型肝炎病毒宫内感染的高危因素。阻断措施目前主要有:(1)孕妇孕晚期注射乙肝免疫球蛋白(HBIG);(2)婴儿主动与被动联合免疫预防;(3)孕晚期联合使用HBIG、乙肝疫苗(HB-Vac)和左旋咪唑涂布剂联合两者治疗;(4)孕晚期使用拉米呋啶降低HBV-DNA水平。更多还原

【Abstract】 The positive maternal serum HBV-DNA,positive maternal serum HBeAg and HBV infection in villous capillary endothelial cells of placenta are the high risk factors of intrauterine infection of HBV.Up to date,interruption measures are mainly:(1)injection of BHIG in pregnant women during late pregnancy;(2)active and possive immunization of infants ;(3)symphysial immunization with HBIG HB-Vac or levamisole liniment during late pregnancy;(4)application of lamivudine in pregnant women during late pregnancy to reduce HBV-DNA level.更多还原