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阿斯匹林联合低分子肝素治疗急性脑梗死近期疗效观察

ASSESSMENT OF EARLY EFFECT OF ASPIRIN COMBINED WITH LOW MOLECULAR WEIGHT HEPARIN (LMWH) ON ACUTE CEREBRAL INFARCTION

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【作者】 王道良陈少霖龙虎

【Author】 Wang Dao-liang, Chen Shao-lin, Long HuShanwei Yihui Foundation Hospital, Guangdong Province 516600 PRC

【机构】 汕尾逸挥基金医院汕尾逸挥基金医院 广东汕尾516600广东汕尾516600广东汕尾516600

【摘要】 目的研究急性脑梗死80例发病6~48h患者应用阿斯匹林联合低分子肝素治疗的有效性和安全性。方法随机分为对照组和治疗组各80例。对照组予阿斯匹林0.1g口服Qd×10d,治疗组追加低分子肝素(速碧林)0.4ml脐周皮下注射Q12h×10d。结果治疗组的神经功能缺损积分明显低于对照组(P<0.01),且未发生颅内出血等严重并发症。结论急性脑梗死发病6~48h的患者使用阿斯匹林联合低分子肝素治疗是有效和安全的。

【Abstract】 Objective To study the efficacy and safety of Aspirin combined with Low Molecular Weight Heparin (LMWH) on 80 patients with acute cerebral infarction in 6~48 hours. Methods Randomized divided into two groups: 80 patients as the control group were given Aspirin (0.1 oral Qd×10 days). And 80 cases as the treatment group were combined with LMWH (Frarparine) (0.4 ml is subcutaneous injected on abdominal wall every 12 hours) for 10 days. Results The Edinburgh Scandinavian Stroke Scale of the treatment group were significantly lower than the control group’s (P<0.01). And there was no severe complication such as cerebral hemorrhage. Conclusion Aspirin combined with LMWH is effective and safe in treating acute cerebral infarction in 6~48 hours.

  • 【分类号】R743.3;
  • 【下载频次】21
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