【摘要】 目的:了解湖州市区外来人口与常住人口肺结核病人的耐药情况。方法:以外来人口为监测组,以常住人口为对照组。对痰涂片阳性病人进行分枝杆菌培养,阳性菌株采用比例法进行4种抗结核药物测试。结果:194例外来人口结核病例中痰培养阳性病人的总耐药率为35.6%,其中初治病人耐药率为29.8%,获得性耐药率50.9%,治愈率为84.8%。200例常住人口结核病例中痰培养阳性病人的总耐药率为29.0%,其中初治病人耐药率为22.3%,获得性耐药率44.3%,治愈率为87.0%。结论:外来人口和常住人口肺结核均处于高耐药状态,继续贯彻现代结核病控制策略,进行全程规则化疗,减少耐药结核病人的发生。更多还原

【Abstract】 Objective:To determine the status of drug resistance for pulmonary tuberculosis in both migrant and resident in Huzhou.Methods:The drug resistance of palmonary tuberculosis were determined in group of migrant TB cases and resident TB cases as control group.Proportional method was used for susceptibility test of 4 antituberculosis drugs.Results:Total drug resistance rate of 194 smear-positive patients was 35.6%,of which the rates of first treat and re-treat patients were 29.8% and 50.9% respectively,and the total cure rate was 84.8% in group of migrant TB case.200 smear-positive patients’ total drug resistance rate was 29.0%,of which the rates of first treat and re-treat patients were 22.3% and 44.3% respectively,and the total cure rate was 87.0% in group of resident.Conclusion:The rate of drug resistance was high in both migrant and resident TB cases,so modern TB control program should be implemented continuously to decrease the occurrence of drug resistance tuberculosis.更多还原