【摘要】 目的:探讨颅脑手术后颅内感染的易感因素与防治措施。方法:对1287例颅脑手术患者的有关临床资料进行分析。结果:颅内感染的发生与多种因素有关。诸如严格的无菌操作、缩短手术时间、减少和避免激素的术前应用、及时治疗并发症、适时拔去术中所置引流管和更换脑室外引流管以及正确处理脑脊液耳鼻和切口漏等。在全身使用大量有效抗生素的同时行鞘内或脑室注庆霉素或头孢噻肟钠收到良好疗效。结论:严格的无菌操作、针对不同的易感因素采取相应的预防措施可减少术后颅内感染的发生。更多还原

【Abstract】 Objective:To investigate the susceptible factors, the methods of prevention and treatment of intracranial infection after craniocerebral operation.Methods:The relevant clinical materials of 1 287 patients with craniocerebral diseases treated surgically in our department from January 1997 to November 2003 were reviewed.Results:Many susceptible factors were revealed to be responsible for the intracrannial infection. The steps of prevention were mainly the strict aseptic manipulation, short surgical procedure, reduction and avoidance of glucocorticoids administration, treatment of complications, proper management of the drainage and cerebrospinal fluid leakage. Antiseptic treatments were mainly intravenous administration of effective antibiotics, simultaneously intrathecal or ventricular injection of gentamycin and cefotaxime.Conclusions:The strict aseptic manipulation and prevention of various susceptible factors may reduce the occurrence of postoperative intracranial infection. Intravenous administration and simultaneous intrathecal or ventricalar injection of antibiotis are important measures for patients complicated with intracranial infection.更多还原