【摘要】 目的:近年来,虽然脑卒中的治疗方法进展很快,但脑卒中后抑郁的发生率高达40%左右。脑卒中后抑郁可影响脑卒中患者神经功能的恢复。因此,认识脑卒中后抑郁有利于脑卒中患者生活质量的提高。资料来源:应用网络www.google.com ,M edline检索近5年内中国医学核心期刊及国外有关脑卒中后抑郁研究的相关文献,检索词:脑卒中,抑郁,发生率,相关因素。资料选择:选择有关脑卒中后抑郁的实验研究及临床研究等相关文献42篇,排除非随机研究原著性文献,未排除非盲法研究原著的文献。资料提炼:在42篇文献中,内容有不同程度重复的有10篇,给予删除;对32篇文献进行分类整理,其中10篇选用为参考文献。资料综合:脑卒中后抑郁的发生率为40%左右,是社会、心理、生物因素共同作用的结果。一般认为,抑郁发生的高危期为脑卒中后一两年,脑卒中后抑郁病程不一。恢复期神经功能缺损程度受脑卒中后抑郁的影响,中重度抑郁可延迟神经功能恢复,脑卒中后抑郁还可导致患者日常生活活动能力恢复差,影响患者的认知功能,增加痴呆的发生率。从临床观察而言,脑卒中后抑郁的治疗已取得明显进展。结论:脑卒中后抑郁的发病率较高,其与多种因素有关。脑卒中后抑郁对神经功能、认知功能及日常生活能力等会产生不良影响。积极的干预与治疗,对降低脑卒中后抑郁的发病率有一定作用。更多还原

【Abstract】 OBJECTIVE: Although the therapeutic method of stroke is progressed very quickly in recent years, the incidence of its post-depression is up to 40%. Poststroke depression many affect neural function recovery, for which, to understand it is advantageous of improving living quality of stroke patients.DATA SOURCE: The literatures relevant to poststroke depression were looked up from China medical nuclear journals and studies at home and abroad in recent 5 years on www.google.com, Medline. The Retrieval words: stroke, depression, incidence, relevant factors.STUDY SELECTION: Totally 42 relevant papers were selected on experimental and clinical studies on poststroke depression. The original literatures of non-randomized study were excluded and those of non-blind study were not excluded.DATA EXTRACTION: Of 42 papers, 10 papers were deleted be-cause of repetition of various degrees and 32 papers were sorted out in category and 10 of those were selected as reference.DATA SYNTHESIS: The incidence of poststroke depression is about 40%, resulting from the co-factors of society, psychology and biology. It is viewed generally that the high risk phase of depression is in a couple of year after stroke and the duration of poststroke depression is various. The severity of neural functional deficits in recovery phase is affected by poststroke depression. Moderate and severe depression may delay the recovery of neural function and poststroke depression can al-so result in poor recovery of daily living capacity of patients, affect patients’ cognition and increase the incidence of dementia. Concerning to clinical observation, a remarkable progression has been achieved on treatment of poststroke depression.CONCLUSION: The incidence of poststroke depression is very high, associated with multiple factors. Poststroke depression influences harm-fully on neural function, cognition and daily living capacity. Active in-tervention and treatment provide a certain action on reducing the inci-dence of poststroke depression.更多还原