【摘要】 背景:缺血性脑卒中发病呈年轻化趋势,因此研究中青年脑卒中的危险因素,进行一级康复预防有着极其重要的临床意义。目的:探讨中青年缺血性脑卒中的危险因素。设计:以诊断为依据的病例-对照分析。单位:一所大学医院的神经内科。对象:脑卒中组100例为1997-07/2000-12中南大学湘雅二医院神经科住院患者,其中青年(<44岁)患者63例,老年前期(45～49岁)患者37例,平均年龄(42.91±6.38)岁。另随机收集同期100例无脑血管病史的外科病患者为对照组,年龄(42.70±2.98)岁,中青年组61例,老年前期组39例。方法:两组进行12项危险因素对照研究,并将中青年和老年前期分别与对照组进行比较。主要观察指标:各组各项危险因素患病率比较。结果:高血压病、高脂血症、心电图异常、脑卒中家族史、眼底动脉硬化、糖尿病、风湿性心脏病是中青年缺血性脑卒中的危险因素。结论:降低血压、血脂水平对预防缺血性卒中发生有极其重要的意义。更多还原

【Abstract】 BACKGROUND:Ischemic stroke has a younger tendency;hence to explore the risk factors of stroke in the middle- aged and youth for primary rehabilitation has extremely important clinical significance.OBJECTIVE:To investigate the risk factor of stroke in the middle- aged and youth.DESIGN:A case- control analysis based on diagnose.SETTING:Department of neurology in a university hospital.PARTICIPANTS:Totally 100 hospitalized patients including the middle- aged and youth(< 44 years old,n=63) and the pre- elderly(45- 49 years old,n=37) with mean age of(42.91± 6.8) were selected into stroke group from the Department of Neurology,Xiangya Second Hospital,Central South University between July 1997 and December 2000.Another 100 surgical patients without history of cerebrovascular diseases aged(42.70± 2.98)including the middle- aged and youth(n=61) and the pre- elderly(n=39) were collected randomly from the same corresponding period as control gruop.METHODS:A comparative study of 12 risk factors between two groups was studied and compared the middle- aged group and youth,the pre- elderly group with control group.MAIN OUTCOME MEASURES:Morbidity comparison of each risk factor in each group.RESULTS:Hypertension,hyperlipemia,abnormal electrocardiogram (ECG),family history of stroke,arteriosclerosis of the eyeground, diabetes,and rheumatic heart disease are risk factors of ischemic stroke in the middle- aged.CONCLUSION:It is extremely important significance to reduce blood pressure and blood- fat level in the prevention of ischemic stroke.更多还原