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运动强度对大鼠肝细胞凋亡的影响

Exercise Intensity and Its Effect on Apoptosis of Rat Hepatocytes

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【作者】 赵咏梅杨建雄

【Author】 ZHAO Yong-mei 1,2,Yang Jian-xong1 (1.The College of Life Science, Shaanxi Normal University,Xi’an 710062, China;2.Department of Life Science ,Xi’an University of Arts and Science ,Xi’an 710065,China)

【机构】 陕西师范大学生命科学院陕西师范大学生命科学院 陕西西安710062 西安文理学院生命科学系陕西西安710065陕西西安710062

【摘要】 论述了肝细胞发生凋亡时的超微结构特征及其动态过程,介绍了肝细胞凋亡过程中SOD ,GSH Px ,MDA及线粒体膜电位的变化,阐明了不同强度运动对肝细胞凋亡的影响,认为大强度运动可诱导肝细胞凋亡,而运动后机体抗氧化能力的下降,是肝细胞发生凋亡的机制之一.

【Abstract】 The ultrastructure and the dynamic morphological process of hepatocyte apoptosis was studied. Changes in the activity of SOD, GSH-Px, the quantity of MDA and the mitochondrial membrane potential was also introduced to prove the relationship between different kinds of exercise intensity and the apoptosis of rat hepatocytes. It is pointed out that exercise can lead to rat hepatocyte apoptosis, which may be the result of decreased antioxidative capability of hepatocytes after exercise.

【关键词】 运动强度肝细胞细胞凋亡抗氧化
【Key words】 exercise intensityhepatocytesapoptosisantioxidative
  • 【文献出处】 西安文理学院学报(自然科学版) ,Journal of Xian Educational College , 编辑部邮箱 ,2005年01期
  • 【分类号】R873
  • 【被引频次】8
  • 【下载频次】117
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