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核酸对铅致大鼠氧化应激的影响
Effect of Dietary Nucleic Acid on DNA oxidative damage of Peripheral Blood Lymphocyte Cells in Rats
【摘要】 目的:研究核酸营养对大鼠外周血淋巴细胞DNA损伤的影响。方法:大鼠灌胃饮食核酸5周后,采用单细胞凝胶电泳技术对外周血淋巴细胞DNA损伤进行分析。结果:核酸组大鼠淋巴细胞DNA的迁移率和尾长均显著低于对照组(P<0.05)。结论:饮食核酸对淋巴细胞DNA损伤具有一定的保护作用。
【Abstract】 Objective:To observe the protective effect of Dietary Nucleic Acid on DNA damage.Method: The rats were given dietary nucleic acid.After 5 weeks,the DNA break in peripheral blood lymphocytes from the rats were analyzed with single cell gel electrophoresis.Results: Compared with control,the damage of DNA in Dietary Nucleic Acid group were reduced significantly(P<0.05).Conclusion: Dietary Nucleic Acid could protect DNA damage of peripheral blood lymphocytes in Rats.
【关键词】 饮食核酸;
大鼠;
DNA损伤;
单细胞凝胶电泳;
【Key words】 Dietary Nucleic Acid; Rat; DNA damage; single cell gel electrophoresis;
【Key words】 Dietary Nucleic Acid; Rat; DNA damage; single cell gel electrophoresis;
- 【文献出处】 微量元素与健康研究 ,Studies of Trace Elements and Health , 编辑部邮箱 ,2005年06期
- 【分类号】R114
- 【被引频次】1
- 【下载频次】74