【摘要】 利用溶剂萃取、薄层层析对大叶紫薇提取物中三萜化合物进行分离,通过 DSC,UV, IR和HPLC/MS对分离产物中具有降血糖的成分 3 进行结构分析,结果表明:以氯仿∶丙酮为展开剂,可在硅胶板中将大叶紫薇中三萜化合物有效分离。对分离出的成分 3,DSC测定其熔点为 283~287 ℃,焓值为43 727 J/g;UV最大吸收波长为 206 nm; MS测定其相对分子质量为 457; IR光谱符合乌苏果烷型结构.经分析,具有降血糖的成分3即为熊果酸.更多还原

【Abstract】 Solvent-extraction and thin-layer chromatography were used to extract and separate triterpene from Lagerstroemia specious L. Structures of the composition #3 were identified by DSC、UV、 IR and HPLC/MS.The results showed that, triterpene can be efficiently separated with thin-layer chromatography using: acetone as the developer. The result also indicated that, the melting point, enthalypy,optimum absorbance wave lenghth, and molccular weight were 283~287 ℃,43.727 J/g, 206 nm, and 45%, respectively. IR spectrum fit that of ursane structure. The result showed compound #3 was ursolic acid.更多还原