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肺癌患者血浆葡萄糖、丙氨酸浓度与体重减轻的关系

Relation between concentration of glucose and alanine in plasm and weight loss of lung patients

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【作者】 李永进周涌宋春梅石玮马洪波王长文刘晓华

【Author】 LI Yong-jin,ZHOU Yong,SONG Chun-mei,SHI Wei,MA Hong-bo,WANG Chang-wen,LIU Xiao-hua(School of Public Health,College of Jilin Medicine Pharmacology,Jilin 132013,China)

【机构】 吉林医药学院公共卫生系吉林医药学院基础护理教研室吉林大学第一临床医学院营养部 吉林吉林132013吉林吉林132013吉林吉林130021吉林长春130021

【摘要】 【目的】研究肺癌患者血浆葡萄糖、丙氨酸浓度与体重减轻的关系。【方法】选取确诊为非小细胞性肺癌的患者,根据体重有无减少分为体重稳定组和体重减轻组,用健康人为正常对照组;调查营养状况、血浆中葡萄糖、丙氨酸的浓度,分析患者血浆葡萄糖、丙氨酸浓度与体重减轻的关系。【结果】被检者食物摄入与发病前无变化,热量、碳水化合物、蛋白质或脂肪的摄入组间无差异,体重减轻组葡萄糖浓度高于体重稳定组患者;体重减轻组肺癌患者血浆丙氨酸浓度低于体重稳定组,(P<0.01)。【结论】体重减轻肺癌患者葡萄糖、丙氨酸代谢发生改变。

【Abstract】 【Objective】To investigate the relation between concentration of glucose and alanine in plasm and weight loss of lung patients.【Methods】Patients with weight loss and without weight loss and heathy control subjects were studied.Nutritional status of them was analyzed and the concentration of glucose and alanine in plasm of them was measured.【Results】Energy,carbohydrate and protein did not differ significantly among the patients groups.Mean glucose in plasm of patients with weight loss was significantly higher than that of patients without weight loss,however,mean alanine in plasm of patients with weight loss was significantly lower than that of patients without weight loss.【Conclusion】Metabolism of glucose and alanine in lung cancer patients with weight loss was changed.

【关键词】 体重减轻丙氨酸葡萄糖肺癌
【Key words】 Weight lossAlanineGlucoseLung cancer
  • 【文献出处】 武警医学院学报 ,Acta Academiae Medicinae Cpapf , 编辑部邮箱 ,2005年06期
  • 【分类号】R734.2
  • 【被引频次】2
  • 【下载频次】71
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