节点文献
酿酒酵母细胞表面工程应用研究新进展
Newly progress in applications of Saccharomyces cerevisiae cell-surface engineering
【摘要】 酿酒酵母表面展示工程是一个新兴的蛋白表达系统,由于它能进行蛋白翻译后修饰,能方便地对表达的蛋白产物进行检测和筛选,近年来应用研究发展迅猛。它在构建全细胞催化剂、抗原/抗体库、生物吸附剂、生物传感器、组合蛋白文库、免疫检测及亲和纯化中取得了很多新的应用,在蛋白质分子的功能研究与应用中发挥了更加重要的作用。
【Abstract】 Saccharomyces cerevisiae cell-surface engineering is a newly genetic expressing system for fusion heterologous gene. With its ability of post-translational modification, and the convenience to identify and screen the expressed products, it is undergoing a marvelous progress in its newly applications, which include using as whole-cell biocatalyst, antigen/antibody library, bioadsorbent, biosensor, combinatory protein library, immunoassays and affinity purification. It performs a more and more important role in exploring the function and application of protein molecules.
- 【文献出处】 微生物学报 ,Acta Microbiologica Sinica , 编辑部邮箱 ,2005年05期
- 【分类号】TS201.3
- 【被引频次】20
- 【下载频次】559