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纳络酮治疗新生儿缺氧缺血性脑病的疗效观察及护理

Observation of curative effect of Naloxone and nursing in the treatment of hypoxic-ischemic encepha lopathy of the newborn

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【作者】 孙丽珍亓冬梅许芬王娜

【Author】 SUN Li-zhen, QI Dnngm-mei, XU Fen, WANG Na Taishan Medical College, Taian 271000, China Affiliated Hospital of Taishan Medical College, Taian 271000, China

【机构】 泰山医学院泰山医学院附属医院泰山医学院附属医院 山东 泰安 271000山东 泰安 271000

【摘要】 目的探讨纳络酮治疗新生儿缺氧缺血性脑病(HIE)的疗效及护理。方法将临床确诊的中、重度66 例HIE随机分为两组,将治疗组33例在给予吸氧,抗惊厥,降颅压及支持疗法的基础上加用纳络酮治疗;对照组给予常规综合治疗。结果治疗组总有效率96.97%;对照组总有效率为84.85%,两组比较,治疗有效率有显著性差异(P<0.01)。结论纳络酮治疗HIE成功率高,疗效显著,副作用小,而保持呼吸道通畅,正确氧疗是治疗成功的关键。

【Abstract】 Objective: To probe Naloxone’s curative effect on hypoxic-ischemic encephalopathy (HIE) of the newborn. Methods: Sixty- six children who moderatelly and severely suffered HIE were divided into two groups stocliastically. The treatment group (thirty- three cases) were given oxygen breathing, anti - conwlsion, skull presure decrease and naloxona at the base of support. The control group (the other thirty-three cases) were only given convention complex therapy. Results: In the treatment group, the total effectiveness rate was 96. 97%, and in the control group, the total effectiveness rate was 84. 85% . There was remarkable difference in the treatment effectiveness ( P <0.01). Conclusion: The effective rate of Naloxone in the treatment of HIE is high and the curative effect is remarkable with light side effect. The key to the effective treatment is to keep the respiratory tract to be unobstructed and the correct oxygen treatment.

【关键词】 纳络酮HIE疗效观察护理
【Key words】 NaloxoneHIEcurative effect observationnursing
  • 【文献出处】 泰山医学院学报 ,Journal of Taishan Medical College , 编辑部邮箱 ,2005年05期
  • 【分类号】R473.72
  • 【下载频次】15
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