【摘要】 目的研究三元一体包装ClO2消毒粉剂杀菌效果和毒性。方法采用悬液定量杀菌试验、能量试验和动物毒性试验进行了观察。结果以含25 mg/LClO2消毒液对悬液内大肠杆菌作用5 min,平均杀灭率为99.96%;12.5 mg/LClO2消毒液对金黄色葡萄球菌作用5 min,平均杀灭率为99.92%;50 mg/LClO2消毒液对枯草杆菌黑色变种芽孢作用10min,平均杀灭率为99.93%;含25%以上小牛血清对其杀灭大肠杆菌效果有轻度影响。以200mg/LClO2消毒液作用5 min,完全破坏悬液内HBsAg的抗原性。将三元一体包装ClO2消毒粉剂于54℃存放120 d,ClO2的下降率为8.2%。小鼠急性经口LD50值大于5000 mg/kg,以100 mg/LClO2消毒液对家兔皮肤刺激试验指数为0.63,属于轻度刺激性。结论三元一体包装ClO2消毒粉剂性能稳定,对细菌繁殖体和细菌芽孢具有良好的杀菌效果,属无毒、低刺激性消毒剂。更多还原

【Abstract】 Objective: To study the germicidal efficacy and toxicity of three components Chlorine Dioxide disinfection powder.Methods: Suspension quantitative germicidal test,capacity test and animal toxicity test were used to carry out observation on them.Results: The average killing rates of Escherichia coli in suspension exposed to the disinfectant solution containing Chlorine Dioxide 25mg/L for 5 min,and Staphylococcus aureus exposed to the solution containing Chlorine Dioxide 12.5mg/L for 5 min were 99.96% and 99.92% respectively.The average killing rate of spores of Bacillus subtilis var.niger exposed to the solution containing Chlorine Dioxide 50mg/L for 10 min was 99.93%.200 mg/L Chlorine Dioxide solution with a 5 min contact time could destroy completely the antigenicity of HBsAg in suspension.After the three components Chlorine Dioxide powder was stored at 54 ℃ for 120 days,its content decreased by 8.2%.The mouse acute oral LD50 was above 5000mg/kg,the rabbit skin irritation test index of solution containing Chlorine Dioxide 100mg/L was 0.63,which belonged to mild irritation.Conclusions: Three components Chlorine Dioxide disinfected powder are chemically stable and kill effectively the vegetative forms of bacteria and bacterial spores.This disinfectant belongs to practically non-toxic class and is slightly irritative to skin.更多还原