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刺梨黄酮的体外抗氧化作用
The Antioxidative Activity of Flavonoids from Rosa roxburghii Tratt
【摘要】 利用化学发光及分光光度法研究了刺梨黄酮对活性氧自由基O2-.,H2O2,DPPH·的清除作用,以及对H2O2诱导的红细胞氧化溶血和肝组织脂质过氧化产物(MDA)形成的抑制作用。结果表明,刺梨黄酮能很好地清除各种活性氧,并能显著抑制红细胞氧化溶血以及肝组织MDA的产生。提示其是一种很好的抗氧化剂。
【Abstract】 The chemical light assay and the colorimetric assay were used to detect the oxygen radicals scavenging capacity of flavonoids from Rosa roxburghii Tratt.The effect of flavonoids from Rosa roxburghii Tratt. on oxidative erythrocyte and malondialdehyde(MDA)in rat hepatocyte were investigated.The result showed that flavonoids of Rosa roxburghii Tratt.could strongly scavenge the oxygen radicals, inhibit the erythrocyte oxidative damage, and decrease the content of MDA in rat hepatocyte remarkably. Flavonoids of Rosa roxburghii Tratt. is a potential antioxidant.
【关键词】 刺梨;
黄酮;
自由基;
抗氧化;
【Key words】 Rosa roxburghii Tratt.; flavonoids; oxygen radicals; antioxidation activity;
【Key words】 Rosa roxburghii Tratt.; flavonoids; oxygen radicals; antioxidation activity;
- 【文献出处】 天然产物研究与开发 ,Natural Product Research and Development , 编辑部邮箱 ,2005年04期
- 【分类号】R285
- 【被引频次】64
- 【下载频次】866