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祛痰合剂的质控方法及初步临床应用研究
Elementary study of the quality control method Qutan mixtures and clinical application
【摘要】 目的:探讨祛痰合剂的质控方法及临床应用。方法:(1)以薄层层析方法对贝母花进行定性分析。(2)以容量分析方法对氯化铵进行定量分析。(3)祛痰合剂与川贝枇杷膏对照治疗咳嗽伴有痰病症的观察。结果:(1)薄层层析条件可满足对制剂的定性分析。(2)氯化铵在80mg/ml~120mg/ml范围内呈良好的线性关系,Y=0.3702+0.7018X,r=0.9999。(3)治疗组164例,男116例,女48例,平均年龄(34.8±10.8)岁,平均病程(4.10±3.42)年。对照组166例,男106例,女60例,服药1周,治疗组总有效率96.7%;对照组总有效率65.0%。结论:该制剂处方组成合理,质量易于控制,服用方便,疗效确切。
【Abstract】 Objective To study the quality control method of Qutan mixtures and clinical application. Methods 1TLC method was made in doing the quality analysis of the BeiMuHua2 Quantity analysis of ammonium chloride was made with volumetric analysis 3Treatment with the using of Qu tan mixtures and ChuanBeiPiPaGao ointment was done in the patient having disease of cough with spit. Results 1 TLC method can meet the request for preparation analysis 2 Between 80 mg/ml~120 mg/ml ammonium chloride has a good linearity Y=0.370 2+0.701 8X r=0.999 9 3Treatment group includes 116 men and 48 women the average age was 34.8 34.8±10.8average disease process was 4.1years4.10±3.42.Control group is totally consist of 166 including 106 men 60 women. After one week’s treatment the total effective in treatment group and control group was 96.7% and 65.0% respectively. Conclusion The prescription of preparation is rational and its quality is easy to control it is convinced to use it and its treatment is effective.
- 【文献出处】 天津医科大学学报 ,Journal of Tianjin Medical University , 编辑部邮箱 ,2005年02期
- 【分类号】R287
- 【下载频次】48