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富马酸福莫特罗滴丸成型工艺的研究
Studies on the preparation for formoterol dropping pills
【摘要】 目的:确立富马酸福莫特罗滴丸的最佳成型工艺。方法:采用正交试验法,对成型工艺条件从滴制温度、滴头口径、滴速、冷凝液温度、滴距等方面进行选择。结果:在滴制温度为80oC、滴头口径1.0/2.0(mm/mm)、冷凝温度为15℃、滴距为2cm时,滴丸成型质量最好。结论:该工艺可行。
【Abstract】 0bject: To establish the optimum preparation process for formoterol dropping pills. Methods: Using orthogonal design, preparation conditions were optimized in processing temperature, dripper size, condensate temperature, dropping distance and so on. Results: The quality of formoterol dropping pills was the best under the condition of processing temperature at 80(~oC), dripper size of 1.0/2.0(mm/mm),Condensate temperature at 15(~oC) and 2 cm distance above liquid level. Conclusion: The preparing process for the formoterol dropping pills was available.
【关键词】 富马酸福莫特罗;
滴丸;
正交试验;
工艺;
【Key words】 formoterol fumarate; dropping pills; orthogonal design; pharmaceutical technology;
【Key words】 formoterol fumarate; dropping pills; orthogonal design; pharmaceutical technology;
- 【文献出处】 天津药学 ,Tianjin Pharmacy , 编辑部邮箱 ,2005年02期
- 【分类号】TQ467
- 【被引频次】12
- 【下载频次】174