【摘要】 目的研究口服米索前列醇(Misoprostol)在减少产后出血量方面的临床意义。方法在摩洛哥TAZA地区医院妇产科阴道分娩的200例产妇随机分为两组,研究组106例,在第二产程胎肩娩出后即口服米索前列醇600μg;对照组94例,在胎肩娩出后静脉予催产素20U。观察产后2h出血量,产后出血的发生率,及药物副作用。结果产后2h出血量,研究组与对照组分别为(140±47)ml和(247±68)ml,产后出血的发生率,分别为1%和4%,两组比较差异有统计学意义(P<0.01)。结论口服米索前列醇较之催产素能明显减少产后出血量,降低产后出血的发生率,且给药方法简便、安全、经济。更多还原

【Abstract】 Objective To investigate the clinical value of reducing the amount of post partum bleeding by oral misoprostol.Methods 200 vaginal delivery cases (TAZA, Moroco, June,2004 to Sep. 2004) were randomrised divided into two groups. The researched group(106 cases) has been given misoprostol 600ug right after the delivery of fetal shoulder in the second stage. meanwhile the contrast group(94 cases) has been given exytocin 20U though venous after the fetal shoulder delivery. Then, observation was performed 2 hours after delivery for amount of bleeding, the incidence rate of post-partum bleeding and the side-effect of the medication.Results The amount of bleeding 2 hours after delivery: researched group and contrast group are (140±47)ml and (247±68)ml respectively. The incidence rate of post-partum bleeding is 1% and 4% respectively. There is a statistic difference between two groups.Conclusion Oral intaken msioprostol plays an important role in reducing the amount of post partum bleeding and decreasing it’s incidence rate. Moreover, the medication method is less complicated, safer and more economical.更多还原