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山香圆含片镇痛作用研究

Studies on the Analgesia Effect of Shanxiangyuan Baccal Tablet

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【作者】 詹怡飞张建军陈娇婷毛友昌王淑珍

【Author】 ZHAN Yi-fei1, ZHANG Jian-jun2, CHEN Jiao-ting1, MAO You-chang1, WANG Shu-zhen1(1.Jiangxi Institute of Traditional Chinese Materia Medica, Nanchang 330006, China; 2.Guangzhou University of TCM, Guangzhou 510405, China)

【机构】 江西昌供国药研究所广州中医药大学江西昌供国药研究所 江西南昌330006广东广州510405江西南昌330006江西南昌330006

【摘要】 目的:研究山香圆含片的消炎、镇痛作用。方法:扭体反应、热板法、二甲苯致小鼠肿胀法、蛋清性大鼠足趾肿胀法、H+所致小鼠腹腔毛细血管通透性实验。结果:山香圆含片能显著降低醋酸所致小鼠扭体反应次数,提高热板所致小鼠痛阈,对二甲苯所致小鼠耳肿胀、蛋清性大鼠足趾肿胀、H+ 所致小鼠腹腔毛细血管通透性提高均具明显的抑制作用。结论:山香圆片具有消炎、镇痛的作用。

【Abstract】 Objective:To study the analgesic eff ect of Shanxiangyuan Baccal Tablet.Methods:Body-twist, hot-plate, inflammation caused by dinc ethy benzene, the foot swelling of rat caused by egg albumin, the effect of the tested drugs on skin capillary permeability induced by hydrogen-ion were observe d in the experiment.Results:Shanxiangyuan Baccal Tablet can markedly reduce th e twisting times of mice and rates caused by acetic acid, increase the pain thre shold caused by hot-plate, inhibit mice’s ear swelling induced by diethyl benzen e, the foot swelling of rat caused by egg albumin and the increase of skin capil lary permeability induced by hydrogen-ion.Conclusion:Shanxiangyuan Baccal Tablet has effect of anti- inflammatory and anagesia.

  • 【文献出处】 时珍国医国药 ,LiShiZhen Medicine and Materia Medica Research , 编辑部邮箱 ,2005年05期
  • 【分类号】R285.5
  • 【被引频次】21
  • 【下载频次】199
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