【摘要】 目的比较直肠癌根治术后放射治疗与单纯手术的疗效。方法回顾性分析直肠癌根治术后150例。术后放射治疗92例,剂量范围45～50Gy;单纯手术58例。组间对比及构成比采用χ2检验。结果全组5年总局部复发率22.0%,术后放疗组和单纯手术组局部复发率分别为16.3%和31.0%,术后放疗显著降低了局部复发率(χ2=4.498,P<0.05);但是术后放疗组和单纯手术组远处转移率分别为34.8%和22.4%,无显著性意义(P>0.05)。结论直肠癌根治术后放射治疗可降低局部复发率,但不能降低远处转移率。更多还原

【Abstract】 Objective To evaluate the impact of postoperative adjuvant radiotherapy, compared with surgery alone for rectal cancer. Methods From April 1996 to April 2000, 92 patients with rectal cancer were treated by radical resection and postoperative radiotherapy (Group S+R) and 58 patients with the same cancer underwent surgery alone (Group S). The dose of radiation ranged form 45 to 50 Gy. χ2 test was used for analysis. Results The 5-year overall local recurrence rate was 22.0%. The 5-year local recurrence rates were 16.3% and 31.0% in Group S+R and Group S, respectively. The local recurrence was evidently reduced in Group S+R (χ2= 4.498, P< 0.05). However, the incidence of remote metastasis was not significant in Group S+R compared with that of Group S ( 34.8% vs 22.4%, P> 0.05). Conclusion Postoperative radiotherapy, though reduces the incidence of local recurrence, dose not reduce the remote metastasis rate.更多还原