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国产聚乙烯醇树脂组织相容性的实验研究

An Experimental Study on Biocompatibility of Domestic Polyvinyl Alcohol Particles

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【作者】 张宏文倪才方冷德嵘

【Author】 ZHANG Hong-wen, NI Cai-fang, LENG De-rong (Dept of Intervention, the Fist Hospital Affiliated to Suzhou University, Suzhou 215006, China)

【机构】 苏州大学附属第一医院介入科南京微创医疗有限公司 苏州215006苏州215006江苏南京210006

【摘要】 目的观察国产聚乙烯醇树酯(PVA)植入家兔背部肌肉后的不同时间材料周围的组织反应情况。方法大耳家白兔10只,在其脊柱一侧背部植入国产PVA,另一侧植入进口PVA,观察术后1、4、12、26、52周材料周围的组织反应情况。结果肉眼观察植入部位无皮下和肌肉组织异常病变,组织病理学检查结果符合国家规定的组织反应程度指标。结论国产PVA的组织相容性良好。

【Abstract】 Objective To study the histopathologic changes of domestic polyvinyl alcohol particles after implanted in back muscle of the rabbits. Methods The domestic PVA was implanted in one side of the back muscle of ten rabbits in another side the import PVA was implanted. The operative local histopathologic changes were observed at the 1 rst, 4 th, 12 th, 26 th, 52 th weeks after operation. Results There was no significant inflammation occurred. Local hypodermic and muscular tissue were normal when observed by visual sight. All postoperative histopathologic changes were within the authoritative ranges. Conclusion The histo-compatibility of domestic PVA is favorable.

  • 【文献出处】 苏州大学学报(医学版) ,Acta Academiae Medicinae Suzhou , 编辑部邮箱 ,2005年01期
  • 【分类号】R318.08
  • 【被引频次】3
  • 【下载频次】98
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