【摘要】 目的比较对乙酰氨基酚直肠栓剂和口服混悬剂对发热患儿的疗效。方法对体温≥38.8℃、发热<72 h、年龄4个月~13岁患儿210例,予对乙酰氨基酚直肠栓剂和口服混悬剂10~15 mg/kg,观察服药后体温变化。结果栓剂组111例,混悬剂组99例,用药后30 min和60~90 min时体温两组均无显著差异,但用药后50 min混悬剂体温较栓剂组低;从用药后体温下降程度看,50 min时和最后体温下降程度两组比较均无显著差异。用药后60~90 min体温下降程度混悬剂组较栓剂组明显。结论对乙酰氨基酚口服混悬剂和直肠栓剂对发热患儿降温作用基本相似,但栓剂较混悬剂效果稍差。直肠给药与口服用药同样可被家长接受。更多还原

【Abstract】 Objective To compare effect of the rectal suppository acetaminophenol with oral suspension in febrific children.Met-(hods) Two hundred and ten children aged from 4 months to 13 years who had fever≥38.8 ℃ in 72 hours, received recommended dosage acetaminophen 10-15 mg/kg and their temperatures were measured. Results There was no significant difference in 30 mi-(nutes) and from 60 to 90 minutes after initial treatment or in 50 minutes drop in temperature or final temperature.But it was significant difference in 50 minutes the time temperature after initial treatment and from 60 to 90 minutes mean temperature decreased.Conclusions There are similar effects on the temperature decreasing in children treated with oral and rectal acetaminophen. But there seems well to be compared oral suspension acetaminophenol with rectum suppository.The rectal route is proved to be as acceptable as the oral among parents.更多还原