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畜禽疫苗佐剂研究进展
Recent Progress in Veterinary Vaccine Adjuvant
【摘要】 畜禽用疫苗主要是亚单位疫苗、减毒或灭活细菌/病毒疫苗,为了使疫苗对动物能达到长效持久的保护,必须使用有效的佐剂。根据不同的作用方式,目前可将佐剂主要分为2大类:疫苗传递系统的佐剂、免疫刺激作用佐剂。本文探讨了近年来畜禽用疫苗佐剂的功能及其发展趋势,概述了其应用研究的进展。
【Abstract】 The veterinary vaccine mainly comprise of either subunit, live attenuated or inactivater bacteria/viruses. These vaccines would require optimal adjuvants and delivery systems to accord long-term protection from infectious diseases in animals. Adjuvants can be broadly divided into two classes, based on their principal mechanisms of action:vaccine delivery systems and immunostimulatory adjuvants. The function and development of adjuvant in animals were dicussed here, and the recent progress in application was also included.
【关键词】 畜禽疫苗佐剂;
免疫刺激剂;
疫苗传递系统;
乳化;
【Key words】 veterinary vaccine adjuvants; immunostimulator; vaccine delivery systems; emulsion;
【Key words】 veterinary vaccine adjuvants; immunostimulator; vaccine delivery systems; emulsion;
【基金】 广州市科技攻关重点项目(2003Z2-E0221);广东省农业攻关项目(2003B21403)
- 【文献出处】 生物技术通讯 ,Letters in Biotechnology , 编辑部邮箱 ,2005年02期
- 【分类号】S859.79
- 【被引频次】7
- 【下载频次】460