【摘要】 目的:根据人类白细胞抗原(HLA)-B基因频率,探讨四川彝族的民族起源。方法:收集四川彝族群体的HLA-B基因频率和已报道国内其他主要民族人群的HLA-B基因数据,运用PHYLIP对HLA-B数据进行聚类分析,主成分分析由SPSS11.0完成。结果:从聚类树型结构图可知,我国主要民族明显分为南北两大群,四川彝族虽处于北方人群一组,但在遗传距离上介于南北方人群之间。主成分分析发现,彝族处于汉藏语系群体之中,与藏族群体关系最近。结论:从HLA-B基因的角度分析,四川彝族的HLA-B遗传特征表现为源于北方,与藏族关系密切。更多还原

【Abstract】 Objective: To study the origin of Sichuan Yi ethnic group according to human leukocyte antigen(HLA)-B gene frequency.Methods: HLA-B gene frequencies of Yi ethnic group and other related Chinese ethnic groups were col-lected.Cluster analysis and principle component analysis were performed by PHYLIP software and SPSS11.0 respective-ly.Results: From the phylogenetic tree formed by cluster analysis,mainly Chinese ethnic groups could be divided into Southern and Northern population.Although Sichuan Yi ethnic group was clustered with the Northern population,the ge-netic distance was between Southern and Northern population.By principle component analysis,Yi ethnic group showed close to Tibetan in the Han-Tibet speaking population.Conclusion: From the clue of HLA-B gene,Yi ethnic group shows the genetic characteristic of Northern Chinese and has a close relationship with Tibetan.更多还原