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大豆苷元β-环糊精包合物的制备和鉴定

Preparation and Characterization of Inclusion Complex of Daidzein with β-cyclodextrin

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【作者】 雷英杰俞玫赵康

【Author】 LEI Ying-jie1,2,YU Mei1,ZHAO Kang1 (1.College of Pharmaceuticals and Biotechnology, Tianjin University, Tianjin 300072, China;2.Department of Biotechnology and Chemical Engineering, Tianjin Institute of Technology, Tianjin 300191, China)

【机构】 天津大学药物科学与技术学院天津大学药物科学与技术学院 天津300072天津理工大学生化学院天津300191天津300072天津300072

【摘要】 采用饱和水溶液法,通过调节溶液pH值制备出大豆苷元-β-环糊精包合物,并用紫外光谱、红外光谱、差示扫描量热和X-射线衍射分析等方法加以鉴定。制备大豆苷元-β-环糊精包合物的产率为90.15%,包合物在水中的溶解度明显大于大豆苷元单体。

【Abstract】 The inclusion complex of daidzein with β-cyclodextrin was prepared through the saturated solution method by means of neutralization and characterized by DSC, IR, UV and X-ray analysis respectively. The average inclusion rate of thecomplex was 90.15% and the water-solubility of inclusion complex was greater than that of daidzein.

【关键词】 大豆苷元β-环糊精包合物
【Key words】 Daidzeinβ-cyclodextrininclusion complex
  • 【分类号】TQ463
  • 【被引频次】9
  • 【下载频次】271
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