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松针提取物抗衰老氧化作用研究
Experimental Study of Pineneedle on Anti-Aging
【摘要】 目的观察松针的抗衰老作用。方法玉米须粗多糖按100、200、400mg/kg连续灌胃3~7d,观察小鼠的存活时间,连续游泳时间和免疫器官重量试验。大鼠连续灌胃20d,测血清LPO含量和SOD活性。结果松针能明显提高小鼠耐氧及抗疲劳能力,增加正常小鼠免疫器官重量,并明显增强小鼠网状内皮系统的吞噬功能。可明显降低老年大鼠血清过氧化脂质(LPO)含量,提高超氧化物歧化酶(SOD)活性。结论松针具有抗衰老作用。
【Abstract】 Objective To evaluate the effect of pineneedle on anti-aging. Methods After the mice were treated with pineneedle 100、200、400mg/kg by administration of p.o for 3~7day continually, the survival time、swimming time and weight of immune organ were investigated. After the aged rats were treated for 20days, the content of serum LPO and the activity of SOD were determined. Results Pineneedle could obviously enhance the anti-fatigue and the hypoxia to lerance ability, increase the weight of immune organ and improve the macrophage function in the mice. In addition,pineneedle significantly decreased the content of serum LPO and increase the activity of SOD in the aged rats. Conclusion Our results indicated that pineneedle has effect on anti-aging.
【Key words】 pineneedle; anti-aging; immune-macrophage function; LPO; SOD;
- 【文献出处】 食品科学 ,Food Science , 编辑部邮箱 ,2005年09期
- 【分类号】R285;
- 【被引频次】76
- 【下载频次】820