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骨髓基质细胞与神经损伤和神经退行性疾病
Bone marrow stromal cells and neural injury and neurodegenerative disease
【摘要】 骨髓基质细胞(bone marrow stromal cells, BMSCs)又名成纤维细胞样克隆形成单位(fibroblast colony-forming units, CFU-F)、间质干细胞(mesenchymal stem cells, MSCs)、间质祖细胞(mesenchymal progenitorcells, MPCs)。本文统一用BMSCs这一概念,对其生物学特性及其神经损伤修复作用进行综述。
【Abstract】 Bone marrow stromal cells(BMSCs) which are the important components to the differentiation andproliferation of blood stem cells are also called fibroblast colony-forming units(CFU-F), mesenchymal stem cells(MSCs) and mesenchymal progenitor cells(MPCs).This review focuses on the biological characteristic and theeffect of BMSCs on the repairing of injuried nerve function.
【关键词】 骨髓基质细胞;
基因治疗;
神经损伤;
神经退行性疾病;
【Key words】 BMSCs; gene therapy; neural injury; neurodegenerative disease;
【Key words】 BMSCs; gene therapy; neural injury; neurodegenerative disease;
【基金】 浙江省自然科学基金(397045)资助
- 【文献出处】 生命科学 ,Chinese Bulletin of Life Sciences , 编辑部邮箱 ,2005年01期
- 【分类号】R741
- 【下载频次】124