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心血管病的活血化瘀治疗与骨髓干细胞动员

Treatment of Cardio-vascular Diseases via Promoting Blood Circulation and Removing Blood Stasis As Well As Mobilization of Stem Cells of Bone Marrow for Them

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【作者】 苏海涂荣祖

【Author】 Su Hai and Tu Rangzu (Department of Heart Diseases of the Second Hospital, School of Medical Sciences of Nanchang University, Nanchang 330006)

【机构】 南昌大学医学院第二附属医院心内科南昌大学医学院第二附属医院心内科 南昌 330006南昌 330006

【摘要】 干细胞研究已成为近年来的医学热点,一些研究表明,骨髓干细胞可以在心脏的环境条件下,横向转化为心肌细胞和血管内皮细胞,修复损伤心肌,尤其是近年发现的一些药物能够动员骨髓干细胞进入外周血液,然后到达损伤心肌中,这一新发现为中医药研究提供了思路。由于临床实践已经证实活血化瘀治疗对缺血性心血管病有良好疗效,那么,活血化瘀治疗是否具有动员骨髓干细胞的作用这一命题就值得深入研究。本文就此进行了深入探讨,以期在现代科学的最新层面上进一步阐明活血化瘀治疗心血管病的机理。

【Abstract】 The research of stem cells has become a hotpoint in the area of medical sciences in recent years. Some research results have shown that stem cells of bone marrows can be transversely transformed into cardiocytes and vascular en-dothelial cells to recover injured myocardium and it is found in the last years, in particular, that some medicines are able to mobilize the stem cells of bone marrow to reach peripheral blood and then injured myocardium. Such new discoveries have provided the study of traditional Chinese medicine with a new train of thought. Now that clinical practice has confirmed that the treatment of promoting blood circulation and removing blood stasis has good curative effect for ischernic cardiovascular diseases, the subject of whether this kink of treatment can play such a role as to mobilize the stem cells of bone marrow is worth deep studies. In this article this subject is deeply discussed in the hope that the mechanisms of the treatment of promoting blood circulation and removing blood stasis for cardiovascular diseases can be further expounded on the basis of the latest research results of modern sciences.

【基金】 国家中医药管理局课题(0405JP34);丹参素和复方丹参滴丸在急性心肌梗死的骨髓干细胞动员作用
  • 【分类号】R259
  • 【被引频次】3
  • 【下载频次】120
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