【摘要】 环肽是一种较线性多肽更为稳定的具有多种生理功能和医药价值的环状多肽,在形成荷尔蒙、抗生素、离子载体系统、抗真菌素、癌制剂以及毒素等方面展现出丰富多样的生物活性,具有重大的应用价值。近年来随着生物技术以及生物学与化学领域的交叉发展,不断有新的环肽被分离并鉴定出来。本文综述了自然界存在的一些环肽及环肽的分离纯化、分析方法,并且对环肽的生物合成机制和化学合成进行了概述。更多还原

【Abstract】 Cyclopeptides have lots of physiological functions and curatorial worthiness,and more steadily than linear peptides.They show great potential at forming hormone、antibiotic、ion-carrier system、antifungal antibiotic、antitumor and toxin.More and more cyclopeptides were separated and identificated with development of biotechnology and chemistry.In this mini-review,some natural cyclopeptides will be introduced,including separationn and analysis,biosynthesis and synthesis.更多还原