【摘要】 [目的]观察干扰素α1b治疗慢性乙型肝炎的临床疗效。[方法]慢性乙型肝炎患者分为两组,治疗组82例,男性68例,女性14例,平均年龄为(31±9)岁。应用干扰素α1b治疗,每次300万单位,肌肉注射,隔日一次,疗程4个月。对照组32例,男性21例,女性11例,平均年龄为(35±12)岁,给予一般保肝药物治疗,疗程4个月。[结果]干扰素α1b治疗组的HBeAg和HBV DNA阳转率(分别为51.5%和49.3%)明显高于对照组(分别为6.5%和8%)。[结论]干扰素α1b是一种治疗慢性乙型肝炎的有效抗病素药物。更多还原

【Abstract】 [Objective] To observe the clinical effect of interferon α1b in treating patients with chronic hepatitis B. [Methods] The patients with chronic hepatitis B were divided into two groups.The treatment group of 82 patients(M 68,F 14,age 35a±9a) received interferon α1b 3MU,im,every other day for 4 months.The control group of 32 patients(M 21,F 11,age 35a±12a) received drugs protecting liver for 4 months.[Results] The seroversal rate of HBeAg and HBV DNA in the treatment group were 51.5%.49.3% respectively,which was much better than that(6.5%,8% respectively) in the control group(P<0.001). [Conclusion] Interferon α1b is an effective antiviral drug in treating chronic hepatitis B.更多还原