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注射用还原型谷胱甘肽在输液中的稳定性研究
Study on compatible stability of Reduced Glutathione for Injection in usual infusions
【摘要】 目的研究注射用还原型谷胱甘肽在葡萄糖注射液和氯化钠注射液中的稳定性,为临床用药配伍提供依据。方法以溶液外观、pH值、还原型谷胱甘肽的含量为考察项目,其中还原型谷胱甘肽的含量用HPLC法测定,考察配伍后各考察项目的变化情况。结果注射用还原型谷胱甘肽与葡萄糖注射液和氯化钠注射液配伍后溶液外观、pH值、含量无显著变化。结论注射用还原型谷胱甘肽可与葡萄糖注射液和氯化钠注射液配伍应用。
【Abstract】 Objective To study the compatible stability of Reduced Glutathione for Injection in two infusions.Methods The changes after matching in appearance,pH,HPLC at different times were determined.Results There were no significant changes after matching.Conclusion Reduced Glutathione for Injection can steadily combine with two infusions.
【关键词】 注射用还原型谷胱甘肽;
输液;
配伍;
稳定性;
【Key words】 Reduced Glutathione for Injection; infusion; compatibility; stability;
【Key words】 Reduced Glutathione for Injection; infusion; compatibility; stability;
- 【文献出处】 齐鲁药事 ,Shangdong Pharmaceutical Industry , 编辑部邮箱 ,2005年07期
- 【分类号】TQ464.7
- 【被引频次】6
- 【下载频次】393