【摘要】 目的建立人参固本口服液中人参皂苷Rg1和Re含量测定的方法。方法色谱柱为C18柱;流动相为乙腈-水(22:78,调甲酸pH至2.4);流速1.0 ml.min-1;ELSD参数:漂移管温度110℃,空气流速3.0 L.min-1。结果人参皂苷Rg1在0.4～2.4μg范围内呈良好的线性关系(r=0.997 0),平均回收率为98.9%,RSD=0.32%;Re在0.2～1.2μg的浓度范围内呈良好的线性关系(r=0.998 6),平均回收率为97.7%,RSD=0.25%。结论用此法分析结果准确可靠,适用于此制剂的质量控制。更多还原

【Abstract】 Objective To establish the method for determination of ginsenoside Rg1 and Re in renshenguben oral liquid.Method The C18 column was used.The mobile phase consisted of acetonitrile-water(22:78,adjusted to pH=2.4 with formic acid),at a flow rate of 1.0 ml.min-1 and the ELSD was used.Results The calibration curves were liner forginsenoside Rg1 within 0.4～2.4 μg(r=0.997 0) and for ginsenoside Re within 0.2～1.2 μg(r=0.998 6).Theaverage recoveries were 98.9%(RSD=0.32%) for ginsenoside Rg1 and 97.7%(RSD=0.25%) for ginsenoside Re,respectively.Conclusion The method is suitable for the determination of ginsenoside Rg1 and Re in renshengubenorall iquid.更多还原