【摘要】 目的　回顾性调查我省住院溃疡性结肠炎(UC)患者的诊断、治疗及逐年就诊情况,探讨近年住院病例UC的特点。方法　全省选取5个大型医院,调查1990～2 0 0 3年期间住院诊断为UC的患者,重新审定入组病例,并填写统一的调查表,调查表内容包括患者的诊断、治疗及逐年就诊情况和同期内镜检出率。结果　筛出住院UC患者共3 5 7例,其中男女之比为1.76∶1,年龄12～77(平均46±14 .2 )岁,97.8%UC患者为活动期,以中度(4 2 .7%)和重度(2 9.4%)为主。初发型(3 7.8%)和慢性复发型(4 8.5 %)多见。主要表现为腹泻、腹痛、血便。治疗上以SASP/ 5ASA (69.2 %)和类固醇激素(4 9.0 %)为主。单纯内科治疗总有效率达87.6%,其中8例(2 .2 %)患者行手术治疗,死亡4例(1.1%)。结论　本组住院UC患者以中重度为主,主要为慢性复发型,结肠镜及粘膜活检对诊断有重要意义。综合治疗效果好,预后较好,手术率、病死率及癌变率均较国外报道低。更多还原

【Abstract】 Objective To investigate retrospectively hospitalized ulcerative colitis(UC)for providing correct diagnosis and proper management of the disease.Methods The cases of hospitalized UC from 5 hospitals in Sichuan Province from 1990 to 2003 were reviewed and diagnostic and therapeutic data were analyzed. Results 357 cases of UC were reviewed.The male to female ration was 1.76∶1.Average age of patients was 46±14.2 years old.In all cases,97.8% were active UC,mild 27.2%,moderate 42.7%,severe 29.4%,and 37.8% were first onset,48.5% chronic relapsing,11.5% chronic persistent,only 2.2% acute fulminant.The most common clinical features were diarrhea(89.1%),abdominal pain(70.3%)and bloody stool(70.9%).SASP/5ASA(69.2%)and steroids(49.0%)is still the major medication used for the treatment of UC.Only 1 case accepted immunosuppressive agents.The remission rate by medicine was 87.6%.The operation rate is 2.2%.The mortality is 1.1%.Conclusion There seem to be a tendency of moderate predominance in UC,and chronic relapsing is the commonest disease type.The operation rate and the mortality were lower than those in west countries.更多还原