【摘要】 应用G6PD ACP ADA AK1和GC Tf同步电泳的方法及GPT凝胶电泳的方法,分别对内蒙古境内鄂温克、鄂伦春、达斡尔族人476份血痕红细胞酶型:GPT、6 PGD、ACP、ADA、AK1和血清型GC、Tf的遗传多样性进行检测。根据所测表型频率分布、计算出基因频率分布,识别能力和累积识别能力,就其多态性特征及其在法医学鉴定中的应用价值进行了分析讨论。同国内外不同资料进行了比较研究,阐明了三群体上述酶型和血清型遗传多样性分布的规律和特点。从血型遗传学角度探讨了鄂伦春、鄂温克、达斡尔族间的族源、血缘关系。被调查人群中未发现各酶型和血清型的变异型。更多还原

【Abstract】 Red cell isoenzymes GPT, 6-PGD, ACP, ADA, AK1 and the serum group GC-Tf are genetic polymorphisms that are inherited according to the Mendelian law of segregation. In this paper, the phenotype frequencies of the GPT, 6-PGD, ACP, ADA, AK1 and GC-Tf have been investigated by the method of typing GPT-ACP-6PGD-ADA-AK1 and Gc-Tf on the same mixed starch agarose gel electrophoresis among seven Chinese nationalities, Ewenki,Oroqen and Dawuor.The distribution of their type frequencies varied with ethnic group and the gene frequencies, DP and CDP were also calculated. The ranges of gene frequencies of Ewenki, Oroqen and Dawuor were: GPT~10.46875-0.47225, 6-PGD~A0.8563-0.8583, ACP~A0.2139-0.2208, ADA~10.9500-0.9596, AK~1(1) 0.9963-1.000, Gc~1 0.64375-0.65445, Tf~c 0.9669-0.96945. The DP were: GPT 0.6288-0.6303, 6-PGD 0.3999-0.4037, Acp 0.4916-0.5187, ADA 0.1487-0.1800, AK1 (0-0.0111), GC 0.5839-0.6029, Tf 0.1147-0.1236. No rare genes of other isoenzymes or serum groups were found.The differences in the distribution of 5 isoenzymes and 2 serum groups in the 3 ethnic groups were analyzed. It was found that there were many similarities in the genetic characters of the Oroqen, Ewenki and Dawuor herdsmen populations addressed in the past "suoluner", showing the possible common blood ties of these 3 populations, which has been recorded in the historical data.更多还原