【摘要】 目的探讨肝硬化患者外周血压变化情况及其与预后的关系。方法按照Child-Pugh分级,将149例肝硬化患者分成Ⅰ、Ⅱ和Ⅲ组,其中A级(Ⅰ组)45例、B级(Ⅱ组)49例、C级(Ⅲ组)55例。比较各组的血压差异。并进行随访血压与生存时间的关系。结果Ⅰ组平均血压为(129.2±8.6)/(76.3±6.6)m m H g;Ⅱ组为(118.1±8.6)/(71.8±5.3)m m H g;Ⅲ组为(101.3±9.1)/(64.2±5.5)m m H g。提示患者血压随Child-Pugh分级增加而下降(P<0.05)。随访发现,外周血压低的患者生存时间更短。结论患者的外周血压直接与肝功能好坏有关。外周血压降低提示患者的预后不佳。更多还原

【Abstract】 Objective To investigate the relationship between the change in blood pressure in cirrhotic patients and their prognosis. Methods A total of 169 cirrhotic patients were divided into 3 groups (I, II and III) according to Child-Pugh grade. The blood pressure of each group was compared. And the relationship between blood pressure and survival time was analyzed through long-term follow-up. Results The blood pressure of group I, II, and III were (129.2±8.6)/(76.3±6.6)mmHg, (118.1±8.6)/(71.8±5.3)mmHg and (101.3±9.1)/(64.2±5.5)mmHg, respec-tively. There was a remarkably decrease in blood pressure from A grade to C grade. Moreover, the individual with hypotension has a shorter survival time than others. Conclusion The blood pressure of cirrhotic patients may has a direct association with liver function and is a biomarker to predict their good or bad prognosis.更多还原