【摘要】 目的了解清远市不同人群感染丙型肝炎病毒的状况及流行病学特征,为制定防控措施提供科学依据。方法随机采集不同健康自然人群和高危人群血液样本,对自然人群按照年龄分为未成年组、成年组,高危人群分性病人群组、吸毒人群组,分别调查并采血用两种酶联免疫吸附试剂检测丙型肝炎抗体,两种试剂检测结果均阳性的判为阳性,一阳一阴再用聚合酶链反应方法进行定性检测确定。两种试剂均阴性的判为阴性。结果自然人群未成年组抗-HCV阳性1人,阳性率为0.10%(1/1029),成年组抗-HCV阳性26人,阳性率为0.46%(4/5645);性病人群组抗-HCV阳性8人,阳性率为4.08%(8/196),吸毒人群抗-HCV阳性206人,阳性率为77.74%(206/265)。结论丙型肝炎在吸毒人群中流行严重,与静脉吸毒有关,注射吸毒是丙型肝炎病毒感染流行的极高危行为,性乱次之。更多还原

【Abstract】 Objective To understand the epidemiological characteristics of HCV infection in various populations in Qingyuan City and provide scientific basis for formulating prevention and control measures. Methods Serum samples were collected from healthy natural populations and groups at high risk . The natural healthy populations were, based on age ,divided into 0～17 age group (1 029 samples) and above 18～age group (5645 samples ); while the groups at high risk were divided into sexually transmitted disease (STD) group (196 samples ) and drug user group (265 samples), and the antibody against HCV was detected by using ELISA with two reagents. The results would be regarded as positive if the both results of ELISA with two reagents were positive and the results would be judged as negative if both results of ELISA with two reagents were negative. In case there was a negative and a positive then PCR would be used for confirmation. Results The was one positive in 0～17 age group with a positive rate of 0.10% and 26 positives in above 18～age group with a positive rate of 0.46%. In the STD group there were 8 positives with a positive rate of 4.08%. while there were 206 positive in drug user group with a positive rate of 77.74%. Conclusion HCV was highly prevalent in the group of drug users and drug injection was the high risk behavior associated with HCV infection. Thus effective measures be taken for control the HCV infection in the group of drug users.更多还原