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食管癌根治术及术后放射治疗192例分析
Analysis of 192 postoperative patients with esophageal carcinoma
【摘要】 探讨食管癌根治术后辅助放射治疗以及影响预后的因素。行根治术食管癌192 例,其中44 例合并术后辅助性放射治疗。192例食管癌根治术后患者5 年总的生存率为29. 5%。1、3 和5 年总的生存率单手术组(72. 0%、39 .5%和29 .1%)与术后放射治疗组(77. 4%、40. 8%和29. 5%)差异无统计学意义,χ2=0 .03,P=0 .993。Ⅰ+ⅡA期1、3和5年总生存率分别为82. 5%、50. 8%和41. 0%,ⅡB期分别为63. 5%、26. 8%和13 .4%,Ⅲ期分别为56%、19.6%和9 .8%,有统计学意义,χ2=17 .28,P=0 .000 2。初步研究结果提示,食管癌根治术后辅助放射治疗对生存率的作用不太明显,应慎重实施;分期是影响食管癌预后的主要因素。
【Abstract】 To investigate the utility of adjuvant postoperative radiotherapy following curative resection for esophageal carcinoma and the factors which affect the survival rate.192 patients suffering from esophageal cancer with curative resection were included in the retrospective study, in which 44 cases received postoperative radiotherapy. The overall 5-year survival rate was 29.5%. The 5-year survival rate of 44 patients with postoperative radiotherapy was 29.5%, compared with 29.1% in the patients with surgery alone. No difference was found in the two groups. The 5-year survival rates of Ⅰ+ⅡA stages,ⅡB stage and Ⅲ stage were 41.0%,13.4% and 9.8%,respectively,χ2=17.28 P=0.000 2.The effect of adjuvant postoperative radiotherapy after the curative resection of the esophageal carcinoma is not clear. The stage is one of the important factors affecting the prognoses.
【Key words】 esophageal carcinoma/radical resection; radiotherapy; retrospective study; survival;
- 【文献出处】 肿瘤防治杂志 ,Journal of Qilu Oncology , 编辑部邮箱 ,2005年09期
- 【分类号】R735.1
- 【被引频次】7
- 【下载频次】63