【摘要】 目的研究膀胱移植及利用移植膀胱行膀胱扩大术的可行性。方法将2周龄Lewis系大鼠(供体:n=30)膀胱移植于同系5周龄大鼠(受体:n=30)大网膜内并分为6组,A、B、C、D组分别于移植后第3、7、14、21日摘出移植膀胱:E、F组于移植后第10天用移植膀胱行膀胱扩大术,3周(E组)及6周(F组)后摘出整个新膀胱。摘出标本均行HE染色。结果移植膀胱成活29只(96.7%)。E、F两组移植膀胱全部成活并成功施行膀胱扩大术。HE染色显示移植膀胱结构正常。结论膀胱游离移植可以成活,用移植膀胱行膀胱扩大术具有可行性。更多还原

【Abstract】 Objective To evaluate whether bladder transplantation can be used for bladder augmentation. Methods Bladders from infantile Lewis rats (less than 14days old, n=30)were excised and transplanted into a pouch created in the distal omentum of a 5-week-old Lewis rat (syngeneic transplantation n=30).Transplanted bladder grafts were harvested 3,7,14,21 days after bladder transplantation in groups A-D. Transplanted bladder grafts in group E and group F were used for bladder augmentation 10 days after transplantation.Each augmented bladder was harvested after 3 weeks in group E and 6 weeks in group F. All transplanted bladders were fixed in formalin and Hematoxyliin-eosin(H&E)staining was used to examine graft survival. Results 29(96.7%)of grafts survived successfully. All grafts in group E and F were transplanted and bladder augmentation was performed successfully. H&E staining showed normal bladder structure in successfully transplanted grafts. Conclusion Bladder free transplantation could be survival and the bladder augmentaton could be performed by the planted bladder.更多还原